Commitment to innovation, excellence, equity, and inclusivity

The Dymecki Lab embraces the core mission of Harvard Medical School, which is to alleviate human suffering by nurturing a diverse group of leaders and future leaders in biomedical inquiry.  Dymecki is dedicated to ensuring excellence in scientific training, innovativeness in experimental approach, and accessibility to tools, reagents, and results. Inclusivity and equity define the lab culture.

Specialization in the Serotonin System Shapes Behavior

and Regulates Homeostasis

The Dymecki lab studies how functional modularity arises within the brain serotonergic neuronal system and dynamically controls diverse processes ranging from respiration and thermal balance to emotional mood state to coping behaviors…

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A SPECIAL ACKNOWLEDGMENT in honor of Jia Jia Mai who advanced the science and careers of many in the Department of Genetics at the Harvard Medical School.

2021 will be a different year for the Dymecki Lab, as Jia Jia Mai, their sole lab manager for over 20 years, has retired.  Standing behind every success of the lab has been Jia Jia, tirelessly working to ensure that we have the best of equipment, reagents, stocks, and mouse colony. She has inspired us all with her high standards, efficient approaches, and devotion to excellence professionally and personally. In this way, all of our work has been enriched. It is with much admiration and gratitude that we wish Jia Jia the very best as she embarks on new adventures.


  • Our latest publication “Sex-Specific Role for Dopamine Receptor D2 in Dorsal Raphe Serotonergic Neuron Modulation of Defensive Acoustic Startle and Dominance Behavior"  is now available at eNeuro. Learn how serotonin-producing neurons and dopamine interact in the brainstem to modulate behaviors, and how this differs in males and females.
  • Our latest publication "A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons" is now available at eLife.
  • Read the recent publication featuring Olga Alekseenko's work in "Serotonergic Modulation of Aggression in Drosophila Involves GABAergic and Cholinergic Opposing Pathways", now available at Current Biology.
  • The Dymecki Lab's work was recently featured in the New York Times article "What Causes SIDS?" by Carrie Arnold, which can be read here.